Two years ago a move towards Republicans among some Hispanic and black voters helped Trump secure a decisive win. That seems to have reversed in these midterms.
Democrats claimed all three House races in the overwhelmingly Hispanic congressional districts along the Texas-Mexico border.
Majority-Hispanic counties moved more than 22 percentage points against Republican Senate candidates, compared with the 2024 presidential election, according to a New York Times analysis.
The change is more than any other major demographic group in the country, data reporter Jeff Adelson said.
The shift comes amid widespread anger at immigration enforcement, with a majority (56%) of Americans saying they have an unfavourable opinion of ICE, according to the Pew Research Center.
Counties with a black majority also moved significantly towards Democratic candidates in Senate races.
The Senate race is on a knife-edge in Mississippi, which has the largest share of black voters of any US state with around 37%.
If Scott Colom can win, he would become the first Democrat elected to the Senate in Mississippi since 1982.